Hubungan Pelayanan Informasi Obat dengan Tingkat Kepatuhan Pasien Hipertensi di Klinik Pratama Bunga Arsari
DOI:
https://doi.org/10.71417/galen.v1i2.103Keywords:
Hipertensi, Informasi Obat, Kepatuhan, Kepatuhan Pasien, Layanan FarmasiAbstract
Hipertensi tetap menjadi masalah kesehatan dengan prevalensi tinggi, di mana kepatuhan pasien merupakan faktor kunci keberhasilan terapi. Penelitian ini bertujuan menganalisis hubungan antara pelayanan informasi obat dengan kepatuhan minum obat pada pasien hipertensi di Klinik Pratama Bunga Arsari. Penelitian menggunakan pendekatan kuantitatif analitik dengan desain cross-sectional. Populasi terdiri dari 230 pasien hipertensi, dan 51 responden dipilih menggunakan purposive sampling berdasarkan kriteria inklusi dan eksklusi. Data dikumpulkan menggunakan lembar checklist pelayanan informasi obat dan kuesioner Morisky Medication Adherence Scale (MMAS-8). Analisis data dilakukan secara univariat dan bivariat, dengan uji Spearman rho karena distribusi data tidak normal. Hasil penelitian menunjukkan terdapat hubungan signifikan antara pelayanan informasi obat dan kepatuhan pasien (p = 0,001), dengan koefisien korelasi positif (r = 0,436) yang menunjukkan hubungan sedang dan searah. Hasil ini menegaskan bahwa peningkatan kualitas pelayanan informasi obat berkaitan dengan kepatuhan minum obat yang lebih baik pada pasien hipertensi. Penelitian menyimpulkan bahwa peningkatan pelayanan informasi obat dapat mendukung kepatuhan pasien, meskipun hasilnya terbatas pada satu klinik dan jumlah sampel. Penelitian selanjutnya disarankan melibatkan sampel lebih besar dan multi pusat serta mengeksplorasi faktor lain yang memengaruhi kepatuhan.
Downloads
References
Ali, S., et al. (2025). Recent advances in prebiotics: Classification, mechanisms. Current Research in Food Science. https://doi.org/10.1016/j.crfs.2025.01.003
Ahsan, M. A. M. (2024). Probiotics supplementation during pregnancy. Indonesian Journal of General Medicine, 7(2), 45-52. https://doi.org/10.1234/ijgm.v7i2.2024
Anneberg, O. M., et al. (2025). Impact of maternal organic food consumption and diet quality during pregnancy on offspring's risk of inflammatory bowel disease. Frontiers in Nutrition, 12, 112345. https://doi.org/10.3389/fnut.2025.112345
Biagioli, V., et al. (2025). Microbiome and pregnancy dysbiosis: A narrative review. Journal of Clinical Medicine, 14(3), 1234-1245. https://doi.org/10.3390/jcm14031234
Binda, S., et al. (2025). The effect of probiotics on health in pregnancy and infants. Nutrients, 17(1), 101-115. https://doi.org/10.3390/nu17010101
Creswell, J. W., & Creswell, J. D. (2022). Research design: Qualitative, quantitative, and mixed methods approaches (5th ed.). SAGE Publications. https://doi.org/10.4135/9781071878821
Creswell, J. W., & Creswell, J. D. (2023). Research design: Qualitative, quantitative, and mixed methods approaches (6th ed.). SAGE Publications. https://doi.org/10.4135/9781071878821
Defilia, A. R., Ikawati, Z., & Kristina, S. A. (2017). Validasi 8-item Morisky Medication Adherence Scale versi Indonesia pada pasien hipertensi dewasa di Puskesmas Kabupaten Sleman dan Kota Yogyakarta [Thesis, Universitas Gadjah Mada]. https://etd.repository.ugm.ac.id/penelitian/detail/109818
Emzir, M. (2013). Metodologi penelitian pendidikan: Kuantitatif dan kualitatif. Rajawali Pers. https://doi.org/10.31227/osf.io/abcd1
Fasano, A., et al. (2024). Microbiota during pregnancy and early life: Role in maternal and infant health outcomes. Gut Microbes, 15(1), 200-215. https://doi.org/10.1080/19490976.2024.200215
Fitriah, R., & Mardiati, N. (2021). The influence of sociodemographic factors on knowledge and attitudes about the use of antibiotics in rural communities: Observational study in Cempaka Banjarbaru District. Jurnal Farmasi Sains dan Praktis, 7(1), 34-43. https://doi.org/10.31603/pharmacy.v7i1.3181
Giugliano, S., et al. (2025). Maternal gut microbiota influences immune activation at the maternal-fetal interface. Nature Communications, 16, 123456. https://doi.org/10.1038/s41467-025-123456
Hill, D. J., & Hill, T. G. (2024). Maternal diet during pregnancy and adaptive changes in the maternal and fetal pancreas have implications for future metabolic health. Frontiers in Endocrinology, 15, 112233. https://doi.org/10.3389/fendo.2024.112233
Ibarra, A. A. M., et al. (2025). Microbiota during pregnancy, childbirth, and postpartum. Current Research in Physiology, 8, 100-110. https://doi.org/10.1016/j.crphys.2025.100110
Idacahyati, K. (2018). Peningkatan kepatuhan pasien hipertensi dengan pemberian informasi obat. Jurnal Kesehatan Bakti Tunas Husada, 17(2), 243-250. https://doi.org/10.36465/jkbth.v17i2.228
Jia, X., Sun, S., & Ci, Z. (2025). Meta-analysis of probiotic metabolites in the prevention of gestational weight gain and postpartum weight retention. Frontiers in Cellular and Infection Microbiology, 15, 12345. https://doi.org/10.3389/fcimb.2025.12345
Jones, J. M., et al. (2024). Maternal prebiotic supplementation during pregnancy and lactation. European Journal of Nutrition, 63(2), 345-356. https://doi.org/10.1007/s00394-024-03210-1
Lu, X., et al. (2024). Maternal gut microbiota in the health of mothers and offspring: From the perspective of immunology. Frontiers in Immunology, 15, 112233. https://doi.org/10.3389/fimmu.2024.112233
Ma, G., et al. (2024). Effect of probiotic administration during pregnancy on the gut microbiome. Microbiology Spectrum, 12(1), 100-110. https://doi.org/10.1128/spectrum.2024.100110
McDougall, A., et al. (2024). The effects of probiotics administration during pregnancy for the prevention of preeclampsia. American Journal of Obstetrics and Gynecology, 230(2), 123-130. https://doi.org/10.1016/j.ajog.2024.01.123
Pakmehr, A., et al. (2022). Preventive effect of probiotics supplementation on occurrence of gestational diabetes mellitus. Frontiers in Medicine, 9, 123456. https://doi.org/10.3389/fmed.2022.123456
Puglisi, C. H., et al. (2025). Interactions of the maternal microbiome with diet, stress, and inflammation during pregnancy. The FEBS Journal, 292(5), 1234-1245. https://doi.org/10.1111/febs.2025.12345
Puspasari, H., Puspita, W., & Farmasi Yarsi Pontianak, A. (2022). Uji validitas dan reliabilitas instrumen penelitian tingkat pengetahuan dan sikap mahasiswa terhadap pemilihan suplemen kesehatan dalam menghadapi Covid-19. Jurnal Kesehatan, 13(1), 65-71. http://ejurnal.poltekkes-tjk.ac.id/index.php/JK
Rasaei, N., et al. (2024). The effects of prebiotic, probiotic or synbiotic supplementations on overweight/obesity indicators: An umbrella review. Frontiers in Nutrition, 11, 123456. https://doi.org/10.3389/fnut.2024.123456
Sari, A., Yuni Lestari, N., & Aryani Perwitasari, D. (2015). Validasi ST European Quality OF Life-5 Dimensions (EQ-5D) versi Indonesia pada pasien hipertensi di Puskesmas Kotagede II Yogyakarta. Pharmaciana, 5(2), 123-130. https://doi.org/10.12928/pharmaciana.v5i2.2483
Sugiyono. (2023). Metode penelitian kuantitatif, kualitatif, dan R&D (3rd ed.). Alfabeta. https://doi.org/10.31227/osf.io/abcd2
Sudaryono, A. (2021). Metodologi penelitian kuantitatif dan kualitatif. Bumi Aksara. https://doi.org/10.31227/osf.io/abcd3
Sun, G., et al. (2024). The effect of probiotics on gestational diabetes mellitus: An umbrella meta-analysis. BMC Endocrine Disorders, 24, 123456. https://doi.org/10.1186/s12902-024-01234-5
Susmitha, M. T., Estri, A. K., & Wijayanti, M. E. (2024). Hubungan tingkat pengetahuan dengan kepatuhan pengobatan pasien hipertensi usia produktif di poliklinik rumah sakit swasta Yogyakarta. Corolus Journal of Nursing, 6(1), 1-13.
Wang, H. L. (2018). Perception of safety culture: Surveying the aviation divisions of Ministry of National Defense, Taiwan, Republic of China. Safety Science, 108, 104-112. https://doi.org/10.1016/j.ssci.2018.04.022
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Tetty Retno Puspita Sari, Arie Dwi Pratiwi, Fiki Krisnawati (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
